Phase 3 Trial for Mydriasis Medication

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COMPLETED STUDY

MIRA – Phase 3 Trial for Mydriasis Medication

Disease/Condition

Pupil Dilation Reversal

Status

Completed

Description

Pharmacologically induced mydriasis, a key aspect of ophthalmologic exams and procedures, can lead to photophobia, discomfort and impairment of vision. Depending on the individual and the color of their eyes, the effects of dilation can last anywhere from 6 to over 24 hours. Currently, there are no available options to safely reverse mydriasis. The MIRA-2 study assessed the efficacy of 0.75% phentolamine ophthalmic solution (POS) to reverse pharmacologically induced mydriasis.

Study Dates

Completed February 2022

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